University of Cambridge
Job title:
PhD Studentship: Modelling of strain-rate effects in pharmaceutical tabletting
Company
University of Cambridge
Job description
Important Note: Please apply for this role through
Funder: Novo Nordisk (home and overseas candidates eligible) Duration: 4 years (start October 2024) Supervisor: Professor James Elliott Closing date: 16 May 2024 Stipend: EPSRC equivalent, £19327 per annum
During early-stage formulation and process development, scientists undergo extensive experimental screening campaigns and, although the tablet failure risk is reduced, there still exist risks that remain undetected and often cause issues during upscaling to production settings, leading to delays and at times undesired process changes. Being able to predict the compaction behaviour at different compression speeds, densities and compositions before formulations are transferred to large-scale production, will be a game changer in the tabletting field. Develop an experimental protocol to investigate the effect of the compression speed, tablet composition and powder characteristics on the tabletting performance.
The main aims of this project are: 1. Improve our existing discrete element model ((VLS-DEM) to enable the compression performance prediction considering the attributes mentioned above 2. Apply the framework to a systematic tablet production upscaling study Applicants should have (or expect to be awarded) an upper 2nd or 1st class honours degree at the level of MSci, MEng (or overseas equivalents) in a relevant subject (Physics, Chemistry, Materials Science, Maths), some programming experience and a willingness to engage with industry throughout the project.
Informal enquiries may be made by email to Professor James Elliott, .
Applications are made through the ‘applicant portal’ at .
Further information on the application process is available from Dr Rosie Ward ( ).
We reserve the right to fill the position with a qualified candidate prior to the conclusion of the advertising period-
Please quote reference LJ40771 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Expected salary
£19327 per year
Location
Cambridge
Job date
Wed, 06 Mar 2024 07:11:47 GMT
To help us track our recruitment effort, please indicate in your email/cover letter where (jobsnear.org) you saw this job posting.